Dr. Shushruth from the Howard Hughes Medical Institute at Columbia University will be giving his seminar, “Building Macaque Models of Human Cognitive Impairments” on Wednesday, December 11th at 9:30 AM in A219B Langley Hall, University of Pittsburgh campus.
Pittsburgh Center for Pain Research and
University of Pittsburgh Brain Institute
Presents a Special Seminar:
“A neural circuit that suppresses pain”
Nicholas Betley, Ph.D.
Department of Biology
University of Pennsylvania
December 11th, 2019
4:00 – 5:00pm
Conference Room 1495 BST
Department of Psychological & Brain Sciences
Synchronizing brain rhythms rescues working memory in older people
Working memory is a set of operations that support the temporary retention of behaviorally significant information and is essential for human cognition. Longitudinal and cross-sectional studies find robust linear decline in working memory across the adult lifespan, contributing to age-related functional impairments. An enduring goal of neuroscience is to understand the neurobiology of working memory and its decline with advancing age. In this talk, I will present new research investigating the large-scale neurophysiology of working memory maintenance that distinguishes younger (18-30 years) from older people (60-76 years). I will focus on rhythmic neural coding schemes grounded in systems neuroscience for how brains compute and communicate information across different temporal and spatial scales during cognition. Further, I will describe how we have developed individually customized, noninvasive neuromodulation methods for augmenting components of rhythmic electrophysiology and rapidly improving working memory performance in older adults. Drug-free noninvasive neuroscience interventions for improving memory in physiological aging and clinical populations are implicated.