Automated, robotic training device developed by Carnegie Mellon undergraduate student advances neuroscience research.
We’ve all heard the saying that individuals learn at their own pace. Researchers at Carnegie Mellon University have developed an automated, robotic training device that allows mice to learn at their leisure. The technology stands to further neuroscience research by allowing researchers to train animals under more natural conditions and identify mechanisms of circuit rewiring that occur during learning.
A research team led by Carnegie Mellon neuroscientist Alison Barth has used the automated technology to identify new, previously unidentified pathways activated when the brain rewires its circuits in response to experience. Their findings are published online in Neuron.
Barth’s lab focuses on understanding the process by which cortical circuits receive sensory information and adapt to it in order to learn. Understanding the algorithm that underlies the changes in the brain’s learning circuitry will have important implications for creating engineered systems that use deep learning and artificial intelligence.
“Neural circuits in the cerebral cortex have had 3.5 billion years to evolve to become perfectly adapted to learning things,” said Barth, a professor of biological sciences and member of the Carnegie Mellon Neuroscience Institute and CNBC. “There is valuable information about what happens in the brain that can be used to inform computations that need to change based on experience.”
To better study how the brain changes during sensory learning, the researchers constructed an army of automated robotic devices, in an effort that was spearheaded by Sarah Bernhard, an undergraduate student in Carnegie Mellon’s Department of Biological Sciences. These devices allowed mice to voluntarily approach a water port in their home cage where they would receive a gentle puff of air to their whiskers followed by a drop of water. If they approached the port and didn’t feel a puff of air, they wouldn’t get a drop of water. Eventually, they learned that a puff of air meant water and they would start to drink when they felt it. Read more…