Papers for the month of August 2018


Frank E Garcea, Jorge Almeida, Maxwell H Sims, Andrew Nunno, Steven P Meyers, Yan Michael Li, Kevin Walter, Webster H Pilcher

"Domain-Specific Diaschisis: Lesions to Parietal Action Areas Modulate Neural Responses to Tools in the Ventral Stream "
Cerebral Cortex, 2018:2018

Mouse over here for a brief summary or click to open article in a new tab.fMRI was used to show that lesions to the left anterior intraparietal sulcus, a region that supports hand-shaping during object grasping and manipulation, modulate tool preferences in left ventral and lateral temporal cortex.


Reddy W., Jay

"Low-loss flexible Parylene photonic waveguides for optical implants"
Optics Letters, 43:4112-4115

Mouse over here for a brief summary or click to open article in a new tab.We demonstrate low-loss optical waveguides in a flexible, biocompatible polymer platform, Parylene C, for use in chronically implantable optical neural probes.


Hennig JA, Golub MD, Lund PJ, Sadtler PT, Oby ER, Quick KM, Ryu SI, Tyler-Kabara EC, *Batista AP, *Yu BM, *Chase SM

"Constraints on neural redundancy"
eLife, 7:e36774

Mouse over here for a brief summary or click to open article in a new tab.Millions of neurons drive the activity of hundreds of muscles, meaning many different neural population activity patterns could generate the same movement. Studies have suggested that these redundant (i.e., behaviorally equivalent) activity patterns may be beneficial for neural computation. Here we leveraged a brain-computer interface to determine what constraints might limit the ability to produce different, behaviorally equivalent neural activity patterns.


Koch, G.E.

"Creatures great and small: Real-world size of animals predicts visual cortex representations beyond taxonomic category"
NeuroImage, 183:627-634

Mouse over here for a brief summary or click to open article in a new tab.This fMRI study reports new evidence that real-world size is represented in early visual cortex using machine learning and representational similarity analyses. We remove a typical confound between size and animal taxonomic category by studying visual activity for (e.g.) insects that are larger than birds and birds that are larger than mammals. We find evidence for a gradient in the ventral stream for the representation of real-world size.


Dutcher, J.M. & Creswell, J.D.

"Behavioral Interventions in Health Neuroscience"
Annals of the New York Academy of Sciences, 0:0

Mouse over here for a brief summary or click to open article in a new tab.Here, we provide a review of behavioral interventions in terms of how they modulate key neurobiological systems, and how modulation of these systems relates to physical health and disease outcomes. We conclude with discussion of opportunities for future research in this promising area of study.


Petersen BA, Nanivadekar AC, Chandrasekaran S

"Phantom limb pain: Peripheral neuromodulatory and neuroprosthetic approaches to treatment"
Muscle and Nerve, epub:epub

Mouse over here for a brief summary or click to open article in a new tab.A review of the neurophysiological causes of phantom limb pain, and an evaluation of the currently available and upcoming neuromodulatory and neuroprosthetic approaches to treating it.


Hooks BM, Papale AE, Paletzki R, Feroze MW, Eastwood BS, Couey JJ, Winnubst J, Chandrashekar J, Gerfen CR

"Topographic precision in sensory and motor corticostriatal projections varies across cell type and cortical area"
Nature Communications, 9:3549

Mouse over here for a brief summary or click to open article in a new tab.How corticostriatal connections of different pyramidal cell types are organized, particularly in convergent circuits, has not been evaluated in detail. Here, cell type-specific Cre-driver mice reveal that pyramidal tract-type corticostriatal projections, though broadly similar to intratelencephalic-type projections from the same cortical region, are generally more restricted and variable in their topographic termination patterns.


Liu, J

"Quantification of the Extracellular Matrix Molecule Thrombospondin 1 and Its Pericellular Association in the Brain Using a Semiautomated Computerized Approach"
J Histochem Cytochem, 66:643-662

Mouse over here for a brief summary or click to open article in a new tab.The structure and functions of the extracellular matrix (ECM), its spatial distribution and pericellular association of ECM molecules remain poorly understood. Colocalization of ECM molecules with cell phenotypes through immunohistochemistry can provide crucial insights into their juxtacrine signaling role as well as their structural relevance to tissue architecture. As manual quantification of images introduces intra- and inter-user bias and is cumbersome for high-throughput approaches, we implemented an automated high-throughput method to quantify the spatial distribution and cellular association of one ECM molecule, thrombospondin 1 (TSP1) with two major cell phenotypes, neurons, and astrocytes. The distribution of TSP1 was homogeneous throughout the striatum and cortex along the anterior–posterior axis. TSP1 occupied 8.85% of the striatum and 7.40% in the cortex. TSP1 also associated with 94.58% and 88.45% of neurons in the striatum and cortex. The association with astrocytes was significantly lower at 47.55% and 28.09%. These findings highlight the key role that TSP1 plays in neuron physiology in a healthy brain, but also highlights key regional difference in astrocytes secreting ECM molecules. The semiautomated approach implemented here will improve the throughput and reliability of measuring the distribution and cellular colocalization of ECM molecules


Helder, A., van den Broek, P., Stafura, J. Z., & Calloway, R. C.

"ERP Indicators of Local and Global Text Influences on Word-to-text Integration"
Language, Cognition and Neuroscience, 33(8):0

Mouse over here for a brief summary or click to open article in a new tab.Both local and global text influences were examined with ERP experiments for their influence of word-to-text integration. Results showed that local-binding processes influence sentence-intitial words.


Alireza Chamanzar, Shilpa George, Praveen Venkatesh, Maysamreza Chamanzar, Lori Shutter, Jonathan Elmer, Pulkit Grover

"An algorithm for automated, noninvasive detection of cortical spreading depolarizations based on EEG simulation"
IEEE Transactions on Biomedical Engineering, 65:1

Mouse over here for a brief summary or click to open article in a new tab.An automated algorithm for noninvasive diagnosis of worsening of brain injuries, stroke, hemorrhages, by detecting cortical spreading depolarizations.


Ware, A. L., Biekman, B., Hachey, R., MacLeod, M. C., Bird, W., Pathak, S., Clarke, E., Hricik, A. J., Puccio, A., Glavin, K., Pomiecko, K., Moretti, P., Beers, S. R., Levin, H., & Wilde, E. A.

"A Preliminary High-Definition Fiber Tracking Study of the Executive Control Network in Blast-Induced Traumatic Brain Injury"
Journal of Neurotrauma, 0:0

Mouse over here for a brief summary or click to open article in a new tab.This preliminary study examined the structure and functional correlates of executive control network (ECN) white matter in Veterans to investigate the clinical utility of using High Definition Fiber Tracking (HDFT) to detect chronic bTBI. Results support anomalous density and integrity of ECN connectivity, particularly of the right DLPFC-putamen pathway, in bTBI.


Mandala, M., Dow, S., Goldberg, M., & Pearlman, J.

"Uncovering the Practices, Challenges, and Incentives for Engineering Design Faculty"
International Journal of Engineering Education, 34(4):1314–1324

Mouse over here for a brief summary or click to open article in a new tab.In a qualitative interview study with 38 design educators and administrators, this study examined the practices and attitudes on teaching design, and any barriers or facilitators they faced, across a sample of schools within the United States. Additionally, the use and faculty attitude on peer review were examined.


"Numerical optimization of coordinated reset stimulation for desynchronizing neuronal network dynamics "
Journal of Computational Neuroscience , (2018) 45:45-58:45-58

Mouse over here for a brief summary or click to open article in a new tab.We perform numerical optimization to find the energy-optimal waveform for desynchronizing neuronal network activity with coordinated reset deep brain stimulation (DBS) with four stimulating electrodes. We also consider possible relevance to DBS for Parkinson’s disease.


Banihashemi, Layla, ODonnell, Christopher, Nimgaonkar, Vishwajit L., Kodavali, Chowdari, McNamee, Rebecca, Germain, Anne

"Using optimal combined moderators to define heterogeneity in neural responses to randomized conditions: Application to the effect of sleep loss on fear learning"
NeuroImage, 181:718-727

Mouse over here for a brief summary or click to open article in a new tab.We analyzed heterogeneity in an fMRI study of sleep restriction/fear extinction using Optimal Combined Moderators (OCMs).

Archive:

  • 2018
  • 2017
  • 2016
  • 2015
  • 2014
  • 2013