Papers for the month of August 2020


Zhiqiang Sha

"Integrative omics analysis identifies differential biological pathways that are associated with regional grey matter volume changes in major depressive disorder"
Psychological Medicine, 072920:1

Mouse over here for a brief summary or click to open article in a new tab.We found convergent alterations of grey matter volume in MDD were associated with transcriptome profiles enriched for synaptic transmission, metabolism, immune processes and transmembrane transport. Genes with abnormal expression in post-mortem tissue in MDD were also associated with transcriptome signatures.


Heitmann, Steward

"Direction-selective motion discrimination by traveling waves in visual cortex"
PLoS Computational Biology, 16:1

Mouse over here for a brief summary or click to open article in a new tab.We create a model for direction selective motion discrimination that uses the competition between two traveling waves. We show that model has a tuning curve that matches those found experimentally.


Ke J., Foley, L.M., Hitchens T.K., Richardson R.M.

"Ex vivo mesoscopic diffusion MRI correlates with seizure frequency in patients with uncontrolled mesial temporal lobe epilepsy"
Human Brain Mapping, 1:1

Mouse over here for a brief summary or click to open article in a new tab.The role of hippocampal connectivity in mesial temporal lobe epilepsy (mTLE) remains poorly understood. The use of ex vivo hippocampal samples excised from patients with mTLE affords mesoscale diffusion magnetic resonance imaging (MRI) to identify individual cell layers, such as the pyramidal (PCL) and granule cell layers (GCL), which are thought to be impacted by seizure activity.This study reveals the potential of mesoscale diffusion MRI to examine layer‐specific diffusion changes and connectivity to determine how these relate to clinical measures. Improving the visualization of intra‐hippocampal connectivity will advance the development of novel hypotheses about seizure networks.


"A Comprehension- or a Production-Based Monitor? Response to Roelofs (2020)"
Journal of Cognition, 3:1-19

Mouse over here for a brief summary or click to open article in a new tab.An up-to-date review of the existing monitoring models in language production, their strengths and weaknesses, and a preview of the next steps in this field.


Hepner, C. R.

"The dual origin of lexical perseverations in aphasia: Residual activation and incremental learning"
Neuropsychologia, 147:107603

Mouse over here for a brief summary or click to open article in a new tab.We show that lexical perseverations in brain damage result from two distinct mechanisms: short-lived residual activation of the previous response, and long-lasting changes to the language production system resulting from incremental learning mechanisms.


Drayton, B., Bernstein, D., & McKenney, S.

"Consequences of curricular adaptation strategies for implementation at scale"
Science Education, NA:1-25

Mouse over here for a brief summary or click to open article in a new tab.The articles examines and compares how developers designed 2 science curricula to support teacher adaptation.


Yu, Byron

"Slow drift of neural activity as a signature of impulsivity in macaque visual and prefrontal cortex"
Neuron, 0:0

Mouse over here for a brief summary or click to open article in a new tab.Perceptual decision-making behavior naturally shifts over time, between a more impulsive and more patient posture. We report here on a brain-wide signal that is present in neuronal populations and reflects the overall level of arousal or impulsivity.


Griffin, Darcy

"The motor cortex uses active suppression to sculpt movement"
Science Advances, 6:N.A.

Mouse over here for a brief summary or click to open article in a new tab.The primary motor cortex (M1) sends a command signal that generates premovement suppression of antagonist muscles. Thus, output neurons in M1 sculpt complex spatiotemporal patterns of motor output not only by actively turning on muscles but also by actively turning them off.

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